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Erved association of CNKSR1 expression and survival outcome suggests scaffolding proteins of the RAS-MAPK pathway may account, in part, for the observed heterogeneity of PDAC biology, and clinically may aid in improved future patient stratification.MethodsStudy participants and tissue microarray (TMA) compositionDe-identified cancer tissues included in this analysis were confirmed to be pancreatic
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Ction, and its ability to promote apoptosis and limit cell proliferation [41], a potentially important function in the present situation given the rapid influx of immune cells following lung infection. Also increased was the Clara cell protein, CC10 or CC16, which is considered to be a marker of lung injury [42] and may have anti-inflammatory activity. Pronounced increases in its levels of express
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Eliminate antibodies that did not recognize the antigenic peptide, (3) antibody binding is blocked by incubation with an excess of the antigenic peptide (preadsorption control), (4) Western blots indicate that the primary bands of labeled protein have molecular weights within the range of those previously observed for glycosylated, dimerized or chaperone protein linked angiotensin receptors [68, 1
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